Tumor regression with a combination of drugs interfering with the tumor metabolism: efficacy of hydroxycitrate, lipoic acid and capsaicin.
Invest New Drugs. 2012 Jul 14. In press
Schwartz L, Guais A, Israël M, Junod B, Steyaert JM, Crespi E, Baronzio G, Abolhassani M.

Toxicity of Carbon Dioxide: A Review.
Chem Res Toxicol. 2011 Dec 19;24(12):2061-70. Epub 2011 Jul 19.
Guais A, Brand G, Jacquot L, Karrer M, Dukan S, Grevillot G, Molina TJ, Bonte J, Regnier M, Schwartz L.

Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Invest New Drugs. 2012 Aug;30(4):1331-42. Epub 2011 Jun 9.
Abolhassani M, Guais A, Sanders E, Campion F, Fichtner I, Bonte J, Baronzio G, Fiorentini G, Israël M, Schwartz L.

The metabolic advantage of tumor cells
Mol Cancer. 10(1):70; 2011.
Israel M and Schwartz L.
Summary – PDF

On the metabolic origin of cancer: substances that target tumor metabolism
Biomedical Research. 22(2):132-66; 2011.
Israël M and Schwartz L.

Ion fluxes, transmembrane potential, and osmotic stabilization: a new dynamic electrophysiological model for eukaryotic cells.
European Biophysics Journal 2010 Nov. 16. [Epub ahead of print]
Clair Poignard, Aude Silve, Frederic Campion, Lluis M. Mir, Olivier Saut and Laurent Schwartz.

Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.
Invest New Drugs. 2010 Oct 8. [Epub ahead of print]
Guais A, Baronzio G, Sanders E, Campion F, Mainini C, Fiorentini G, Montagnani F, Behzadi M, Schwartz L, Abolhassani M.

A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results.
Oncol Rep. 23:1407-16; 2010.
Schwartz L, Abolhassani M, Guais A, Sanders E, Steyaert JM, Campion F, Israël M.

Carbon dioxide is largely responsible for the acute inflammatory effects of tobacco smoke.
Inhal Toxicol. 22:543-51; 2010.
Schwartz L, Guais A, Chaumet-Riffaud P, Grévillot G, Sasco AJ, Molina TJ, Abolhassani M.

Is inflammation a consequence of extracellular hyperosmolarity?
J Inflamm (Lond). 23;6:21; 2009.
Schwartz L, Guais A, Pooya M, Abolhassani M.

Carbon dioxide inhalation causes pulmonary inflammation.
Am J Physiol Lung Cell Mol Physiol. 296:L657-65; 2009.
Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L.

Hyperosmolarity causes inflammation through the methylation of protein phosphatase 2A.
Inflamm Res. 57:419-29; 2008.
Abolhassani M, Wertz X, Pooya M, Chaumet-Riffaud P, Guais A, Schwartz L.

Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A.
Am J Physiol Gastrointest Liver Physiol. 295:G934-41; 2008.
Schwartz L, Abolhassani M, Pooya M, Steyaert JM, Wertz X, Israël M, Guais A, Chaumet-Riffaud P.


The toxicity of carbon dioxide inhalation. Ramazzini days, 25-26 october 2008, Carpi, Italy. 2008 TOBACCO2 Ramazzini Poster

The toxicity of Smoking is Because of Carbon Dioxide : Experimental Evidence. AARC 100th annual meeting, 18-22 april 2009, Denver, CO, USA. 2009 TOBACCO2 Poster AARC


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